THE BONE MARROW ON STERNAL ASPIRATION IN MULTIPLE MYELOMA

The bone marrow on sternal aspiration in multiple myeloma.

The sternal marrow aspiration of amyloid in multiple myeloma.

By SIDNEY TRUBOWITZ, M.D. T HE OCCURRENCE of amyloidosis in multiple myeloma has been long recognized and the association of the two conditions well established. In 1931, Magnus-Levy’ wrote : ‘ ‘When I, at first purely out of interest in the clinical and metabolic aspects of myeloma, dug deeper into the literature, I was surprised to find a rather large, constantly growing body of data on amylo...

Ultrasound-guided sternal bone marrow aspiration

Leebeek FW. Myeloproliferative disease in the pathogenesis and survival of Budd-Chiari syndrome. Haematologica 2006;91: 1712-3. 3. Valla D, Dhumeaux D, Babany G, et al. Hepatic vein thrombosis in paroxysmal nocturnal hemoglobinuria. A spectrum from asymptomatic occlusion of hepatic venules to fatal Budd-Chiari syndrome. Gastroenterology 1987;93:569-75. 4. Hillmen P, Lewis SM, Bessler M, Luzzatt...

The Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Diagnosis of Bone Marrow Metastases

Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...

In vitro Effect of Pomalidomide on Bone Marrow Mononuclear Cells from Multiple Myeloma Patients

Background: Many features of anticancer drugs, including cytotoxicity and/or cytokine induction, are studied using cell lines orhuman blood leukocytes. However, in a disease such as multiple myeloma, most cancerous cells are resided within bone marrowmononuclear cells. In the present study, we investigated the effect of pomalidomide on apoptosis and IL-2 production of bonemarrow mononuclear cel...